MYP_137013
Basic Information
Dermaseptin-3 (DStar 03)
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Antimicrobial Antifungal Anti-Candida
Immunology Innate immune defense Host defense peptide Defense peptide
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytolysis / cell lysis Cytolytic activity
Toxicity / Safety Negative safety assay result Non-hemolytic
Standard
30 amino acids
C141H231N39O39S
Standard
Sequence
GLFKTLIKGAGKMLGHVAKQFLGSQGQPES
Physicochemical Analysis
3128.65 Da
10.00
2.85
2.59
0.0949
-0.14
0.64
0.13
34.62
81.33
0.0667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1258.45
-12.57
42.0
44.0
109.0
220.0
4.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0366647 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Dermaseptin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Paracoccidioides brasiliensis
RECORD: Rec_0377893 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Dermaseptin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal Hemolytic
RECORD: Rec_0406966 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Dermaseptin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
RECORD: Rec_0425691 VERIFIED: NO
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]; Phyllomedusa trinitatis [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic
S. aureus, E. coli, C. albicans
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