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MYP_137013
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Basic Information
Dermaseptin-3 (DStar 03)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
30 amino acids
C141H231N39O39S
Standard
Sequence
GLFKTLIKGAGKMLGHVAKQFLGSQGQPES
Physicochemical Analysis
3128.65 Da
10.00
2.85
2.59
0.0949
-0.14
0.64
0.13
34.62
81.33
0.0667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1258.45
-12.57
42.0
44.0
109.0
220.0
4.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0154210 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Dermaseptin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ3945
RECORD: Rec_0170197 VERIFIED: NO
Provenance & Taxonomy
Phyllomedusa trinitatis [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal
Qualitative functional evidence
PMID29980138 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29980138/; https://www.uniprot.org/uniprotkb/C0HLC5/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0173216 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0190275 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Dermaseptin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
Candida albicans and Paracoccidioides brasiliensis
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP01675
RECORD: Rec_0225304 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Dermaseptin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
Staphylococcus aureus
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP01675
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