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MYP_136998
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
38 amino acids
C174H287N57O44S7
Standard
Sequence
GPLSCGRNGGVCIPIRCPVPMRQIGTCFGRPVKCCRSW
Physicochemical Analysis
4105.95 Da
9.57
5.70
5.41
0.1500
0.07
0.69
0.00
55.11
63.95
0.0526
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1594.25
-17.94
62.0
57.0
126.0
282.0
8.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0382609 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ML35
PaperPurification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.
RECORD: Rec_0394945 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
5-34; 12-27; 17-35
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0403862 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperSelsted M.E., Tang Y.-Q., Morris W.L., McGuire P.A., Novotny M.J., Smith W., Henschen A.H., Cullor J.S.;. "Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils."; J. Biol. Chem. 268:6641-6648. Evidence URLhttps://www.uniprot.org/uniprotkb/BD12_BOVIN/entry
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