Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length411 amino acids

Chemical FormulaC2040H3261N529O568S14

DescriptionStandard

        MFLSVRLLLLLAVLAPVTSTTNPGVKVKLTQKGLEYGRQLGMIQIQQKLKTIKVPDISGSQKVSPIGKVQYSLTNMHIVNVGLPKSGLGLVPGTGVRLSIGNAFISLNGNWRVKYLRFIKDHGSFDLKVSGLTIGTTIIIQSDETGRPRVSSTNCAATVGGADIKFHGGASWLYNLFRNFIDKALRSALQKQICPLVVDAISDLNPQLKTLNVLAKVDQYAEIEYSMVSSPTVSKSSIDFGLKGVFYNIGKHQEPPFSPAVFSLPPQINNMLYVGMSTFTINSAAFVYNSAGALSLYITDDMIPAGSPIRLNTRTFGAFIPQLSKLFPGLMMKLLVKTAKTPVISFQPNNVTVQASGTVTAYAIQPNATLSPLFVLNLVLCACVPFLQWFYFTVCFRVKTGGITEKDKERN
    

Molecular Weight44734.83 Da

Isoelectric Point (pI)9.78

Net Charge (pH 7.0)19.79

Net Charge (pH 7.4) 19.22

Charge Density (pH 7.0) 0.0482

GRAVY Index0.21

Hydrophobic Moment 0.80

Boman Index0.16

Instability Index32.68

Aliphatic Index 102.65

Aromaticity 0.0900

Extinction Coeff. Reduced 34380.00

Extinction Coeff. Oxidized 34630.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0027769 VERIFIED: NO

Provenance & Taxonomy

OrganismSphaeramia orbicularis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria