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MYP_136883
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
20 amino acids
C108H165N33O28
Standard
Sequence
AGPDTPSQFRKKWNKWALSR
Physicochemical Analysis
2373.67 Da
11.10
3.79
3.60
0.1897
-1.44
0.52
-0.33
33.83
29.50
0.1500
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1016.25
-10.08
36.0
32.0
75.0
169.0
7.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0095502 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 60.0%, E 0.0%, T 25.0%, C 15.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0113728 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0299282 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Adrenomedullin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Hormone Vasoregulatory peptide
Evidence URLhttps://www.uniprot.org/uniprotkb/ADML_MOUSE/entry
RECORD: Rec_0348441 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0362720 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Proadrenomedullin N-20 terminal peptide
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Antibacterial Hormone Endocrine Vasoactive Vasodilator Vasoconstrictor Cardiovascular Reproductive regulator Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PMID15489334 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15489334/