Peptide Database

Peptide NameLL-37(17-29) (C-terminal fragment of LL-37, LL; Human, mammals, animals)

Function Ontology

Anticancer

Anticancer ▸ Antitumor

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC80H135N25O17

DescriptionStandard

        FKRIVQRIKDFLR
    

Molecular Weight1719.09 Da

Isoelectric Point (pI)11.72

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.2892

GRAVY Index-0.44

Hydrophobic Moment 0.97

Boman Index-0.39

Instability Index18.70

Aliphatic Index 112.31

Aromaticity 0.1538

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 730.65

LogP -3.72

H-bond Donors 27.0

H-bond Acceptors 21.0

Rotatable Bonds 61.0

Heavy Atoms 122.0

Ring Count 2.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416337 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiviral Anticancer Antiparasitic Anti-inflammatory

TargetSalmonella Typhimurium KCTC 1926

Activity16 μM

MethodMIC

RECORD: Rec_0425456 VERIFIED: YES