Peptide Database

Peptide NamePyocin large subunit

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length480 amino acids

Chemical FormulaC2270H3559N631O715S15

DescriptionStandard

        MGDKATCPKCGKVGTIIEGLPSFIIHGKPAALDGYIIACGCPAKSNRIIAANSRLFADDTRGSSRASSSASHSFSAEEPQADAASPSSPMANSLNSSETMGVIPVFAKSCLRGSGCTDAGSDTESVSNFGKVGFYQIAAGAAVAKVGAAATESLGTTAFRTVGGAATRMISGRWMTPSPWTVGLFGTFYSEKLNSDEQDFIDNSRLAEIATQRGTATTRLRFQWVTNGITGKPEVKGYHTGNGSISDQVPVRSMTKNLGTGGYEFWEDGAKGPSLLWTPGSPDFELPKDTGNSEVFVPPPTILIIPEPTETGGYTETLPMPDEKNFRDYILVHPDGAFEPIYIYLSKPPVELLEVDLYGNFDGRSREGKYHADHMPSSAAVEAYLIRLNPETSPRQISEAVSNVASIIIPKEIHQRISETFGGRNQPYVIDRDSRDLRAALDRNLDAIKSALLEHGITKQQIESARAKMHKLNSEQGLYK
    

Molecular Weight51610.32 Da

Isoelectric Point (pI)5.81

Net Charge (pH 7.0)-6.70

Net Charge (pH 7.4) -7.58

Charge Density (pH 7.0) -0.0140

GRAVY Index-0.35

Hydrophobic Moment 0.68

Boman Index0.02

Instability Index42.68

Aliphatic Index 73.04

Aromaticity 0.0771

Extinction Coeff. Reduced 48360.00

Extinction Coeff. Oxidized 48735.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0204660 VERIFIED: YES

Provenance & Taxonomy

OrganismLeminorella richardii [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)