MYP_136721
SAU-7
Anticancer
Anticancer
▸
Antitumor
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antibiotic activity
Antimicrobial
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Antifungal
Immunology
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Innate immune defense
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Host defense peptide
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Defense peptide
Immunology
▸
Innate immune defense
▸
Host defense peptide
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Host defense activity
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Toxicity / Safety
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Negative safety assay result
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Non-hemolytic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
▸
Toxic
Standard
13 amino acids
C71H113N15O19
Standard
GLFDIIKKIAESF
1480.75 Da
6.07
-0.24
-0.45
-0.0183
0.67
0.71
0.30
20.48
127.69
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
559.39
-1.87
19.0
19.0
51.0
105.0
2.0
12.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0231906
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Acetylation
Amidation
The Ⓧ (position: 2 and 6) in sequence indicates S5 (2-amino-2-methylhept-6-enoic acid). Ⓧ (2) and Ⓧ (6) are cross-linked by hydrocarbon stapling respectively
Bio-Activity Profile
Antifungal
Candida krusei ATCC 2340
>128 μg/mL
MIC
RECORD: Rec_0234925
VERIFIED: YES
Provenance & Taxonomy
Litoria raniformis [Animal]
Aurein
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Anticancer
Antitumor
Anti-Gram-positive
Anti-Gram-negative
[ Refer PubMed 10951191 : - B.cereus (
12 μg/mL
MIC
RECORD: Rec_0239777
VERIFIED: YES
Provenance & Taxonomy
Ranoidea raniformis [Animal]
116057
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antifungal
Anticancer
Staphylococcus epidermidis
50 μg/mL
MIC
RECORD: Rec_0240322
VERIFIED: YES
Provenance & Taxonomy
Litoria raniformis [Animal]
Aurein
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Anticancer
Antitumor
Anti-Gram-positive
Anti-Gram-negative
[ Refer PubMed 10951191 : - B.cereus (
50 μg/mL
MIC
RECORD: Rec_0242724
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Acetylation
Amidation
The Ⓧ (position: 2 and 6) in sequence indicates S5 (2-amino-2-methylhept-6-enoic acid). Ⓧ (2) and Ⓧ (6) are cross-linked by hydrocarbon stapling respectively
Bio-Activity Profile
Antifungal
Candida tropicalis 895
16 μg/mL
MIC
Showing 5 records on this page · Page 21 of 37