Peptide Database

Peptide NameCycloviolacin O5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC124H198N32O41S6

DescriptionStandard

        PCGESCVYLPCLTTIVGCSCKNNVCYTN
    

Molecular Weight2985.48 Da

Isoelectric Point (pI)6.23

Net Charge (pH 7.0)-0.10

Net Charge (pH 7.4) -0.25

Charge Density (pH 7.0) -0.0036

GRAVY Index0.41

Hydrophobic Moment 0.32

Boman Index0.18

Instability Index25.64

Aliphatic Index 72.86

Aromaticity 0.0714

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1160.44

LogP -14.99

H-bond Donors 46.0

H-bond Acceptors 47.0

Rotatable Bonds 91.0

Heavy Atoms 203.0

Ring Count 4.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052178 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)