Peptide Database

Peptide NameNeutrophil cationic peptide 1 type B (GNCP-1B) [Cleaved into: Neutrophil cationic peptide 1 (Corticostatic peptide GP-CS1) (CP-1) (GPNP) (Neutrophil defensin)]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC452H718N134O133S10

DescriptionStandard

        MRTVPLFAACLLLTLMAQAEPLPRAADHSDTKMKGDREDHVAVISFWEEESTSLQDAGAGAGRRCICTTRTCRFPYRRLGTCIFQNRVYTFCC
    

Molecular Weight10478.00 Da

Isoelectric Point (pI)8.22

Net Charge (pH 7.0)1.62

Net Charge (pH 7.4) 1.18

Charge Density (pH 7.0) 0.0174

GRAVY Index-0.15

Hydrophobic Moment 0.67

Boman Index-0.05

Instability Index51.53

Aliphatic Index 69.35

Aromaticity 0.0860

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4298.36

LogP -45.30

H-bond Donors 161.0

H-bond Acceptors 147.0

Rotatable Bonds 340.0

Heavy Atoms 729.0

Ring Count 15.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0094699 VERIFIED: YES

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10141

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic