Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length199 amino acids

Chemical FormulaC1034H1599N251O283S9

DescriptionStandard

        MVSTPTVSNSSVDMSLKGEFFNTGKHQEPPFFPAKFFLPSQTNNMLYIGVSVFTANSAAFVYNKAGVLSLYITDDMVSNKASRNTEVKLSIPYYIYFHDFTLNNFLQLFLQQIPRTITICLNTTAFEVFLPKLVRLFPGLMMKLLVKSVKTAIFTFKPNNVTLQTTGTVTAYAIQPNATLFPLFVLNLMGHQCERPTLS
    

Molecular Weight22362.85 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)5.74

Net Charge (pH 7.4) 5.31

Charge Density (pH 7.0) 0.0289

GRAVY Index0.23

Hydrophobic Moment 0.63

Boman Index0.19

Instability Index28.76

Aliphatic Index 91.56

Aromaticity 0.1307

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10555.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8507.14

LogP -106.64

H-bond Donors 289.0

H-bond Acceptors 301.0

Rotatable Bonds 707.0

Heavy Atoms 1577.0

Ring Count 42.0

Amide Bonds 221.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024307 VERIFIED: NO

Provenance & Taxonomy

OrganismBetta splendens [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence