Peptide Database

Peptide NameToxin HaTx2

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC181H264N48O50S6

DescriptionStandard

        ECRYLFGGCKTTADCCKHLGCKFRDKYCAWDFTFS
    

Molecular Weight4104.71 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.86

Net Charge (pH 7.4) 1.54

Charge Density (pH 7.0) 0.0532

GRAVY Index-0.34

Hydrophobic Moment 0.50

Boman Index-0.07

Instability Index20.16

Aliphatic Index 28.00

Aromaticity 0.2000

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1595.65

LogP -14.49

H-bond Donors 64.0

H-bond Acceptors 59.0

Rotatable Bonds 132.0

Heavy Atoms 285.0

Ring Count 9.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0133452 VERIFIED: NO

Provenance & Taxonomy

OrganismGrammostola spatulata [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0385539 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 8.6%, E 17.1%, T 37.1%, C 37.1% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic