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MYP_136492
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Basic Information
Insulin
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Metabolic ▸ Glucose metabolism ▸ Antidiabetic ▸ Hypoglycemic
Standard
51 amino acids
C257H387N65O76S6
Standard
Sequence
GIVEQCCTSICSLYQLENYCNFVNQHLCGSHLVEALYLVCGERGFFYTPKT
Physicochemical Analysis
5795.60 Da
5.39
-2.12
-2.52
-0.0415
0.22
0.44
0.18
12.32
85.88
0.1373
5960.00
6335.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2264.85
-20.89
83.0
82.0
185.0
404.0
10.0
56.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0069308 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; Rattus norvegicus [Animal]
9606; 10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
6A-11A; 7A-7B; 19B-20A
Bio-Activity Profile
-
RECORD: Rec_0100012 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; Saccharomyces cerevisiae [Fungus]; Escherichia coli [Bacterium]
Insulin
9606;4932;562
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
A6-A11, A7-B7, A20-B19
Sequence identical to human insulin
Bio-Activity Profile
Antidiabetic Hypoglycemic Insulin
PaperPubMed-linked source references: PMID:22960692 PMID22960692 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22960692/
RECORD: Rec_0251959 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; Escherichia coli [Bacterium]
Insulin
9606;562
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
A6-A11, A7-B7, A20-B19
Sequence identical to human insulin; protamine/zinc formulation
Bio-Activity Profile
Antidiabetic Hypoglycemic Insulin
PaperPatent-linked source references: US4430266 Evidence URLhttps://patents.google.com/patent/US4430266 PatentUS4430266
RECORD: Rec_0425644 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; Sus scrofa [Animal]
Insulin
9606;9823
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
A6-A11, A7-B7, A20-B19
Porcine insulin sequence
Bio-Activity Profile
Antidiabetic Hypoglycemic Insulin
PaperPubMed-linked source references: PMID:25941658; PMID:24673155; PMID:24118819; PMID:23448197; PMID:28250698; PMID:28295934; PMID:28282219; PMID:28275957; PMID:28234565 PMID25941658;24673155;24118819;23448197;28250698;28295934;28282219;28275957;28234565 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25941658/