Peptide Database

Peptide NameBeta-defensin 2 (Fragment)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC120H177N37O29S5

DescriptionStandard

        GGSCHFGGCPFHLVKVGRCFGFRSCC
    

Molecular Weight2762.24 Da

Isoelectric Point (pI)8.82

Net Charge (pH 7.0)2.88

Net Charge (pH 7.4) 2.51

Charge Density (pH 7.0) 0.1109

GRAVY Index0.42

Hydrophobic Moment 0.47

Boman Index0.18

Instability Index76.81

Aliphatic Index 37.31

Aromaticity 0.1538

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1029.67

LogP -11.64

H-bond Donors 42.0

H-bond Acceptors 39.0

Rotatable Bonds 85.0

Heavy Atoms 191.0

Ring Count 7.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0025839 VERIFIED: NO

Provenance & Taxonomy

OrganismPasser domesticus [Animal]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0344139 VERIFIED: YES

Provenance & Taxonomy

OrganismPasser domesticus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)