Peptide Database

Peptide NameInsulin-like growth factor

Function Ontology

Annotation / Sequence feature ▸ Secretory pathway ▸ Secreted peptide

Annotation / Sequence feature ▸ Secretory pathway ▸ Secreted protein

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC24H29N7O7

DescriptionStandard

        WGHE
    

Molecular Weight527.53 Da

Isoelectric Point (pI)5.47

Net Charge (pH 7.0)-1.14

Net Charge (pH 7.4) -1.40

Charge Density (pH 7.0) -0.2862

GRAVY Index-2.00

Hydrophobic Moment 0.36

Boman Index0.04

Instability Index-18.43

Aliphatic Index 0.00

Aromaticity 0.2500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 232.39

LogP -0.96

H-bond Donors 8.0

H-bond Acceptors 7.0

Rotatable Bonds 14.0

Heavy Atoms 38.0

Ring Count 3.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084025 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyInsulin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0105824 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 0.0%, T 0.0%, C 100.0% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication

RECORD: Rec_0208929 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyLow molecular weight growth-promoting factor

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Myotropic Receptor modulation Immunomodulatory

Half-LifeMammalian: 2.8 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0218331 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyLow molecular weight growth-promoting factor

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Myotropic Receptor modulation Immunomodulatory

Targetsmooth muscle

Half-LifeMammalian: 2.8 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0396344 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyCystatin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Secreted peptide Secreted protein