Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC221H343N63O72S6

DescriptionStandard

        RPGDAQGPDSCNHGGGLCRVGTCVSGEYPAQYCFEPIILCCKNLPPATTE
    

Molecular Weight5226.86 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-2.20

Net Charge (pH 7.4) -2.55

Charge Density (pH 7.0) -0.0440

GRAVY Index-0.29

Hydrophobic Moment 0.45

Boman Index0.05

Instability Index46.89

Aliphatic Index 56.60

Aromaticity 0.0600

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2115.45

LogP -26.50

H-bond Donors 75.0

H-bond Acceptors 77.0

Rotatable Bonds 159.0

Heavy Atoms 362.0

Ring Count 10.0

Amide Bonds 53.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0016103 VERIFIED: YES

Provenance & Taxonomy

OrganismCyanistes caeruleus [Animal]

FamilyDefensin

Tax ID156563

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

PaperLocus-specific protocol for nine different innate immune genes (antimicrobial peptides: β-defensins) across passerine bird species reveals within-species coding variation and a case of trans-species polymorphisms [PMID:21676198] PMID21676198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21676198/

RECORD: Rec_0304465 VERIFIED: NO