Peptide Database

Peptide NameDaptomycin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard Statusnot Standard

Sequence Length13 amino acids

Chemical Formula-

Descriptioncontains X representing unresolved or non-standard residue

        WNDTGXDADGSXX
    

Molecular Weight0.00 Da

Isoelectric Point (pI)0.00

Net Charge (pH 7.0)0.00

GRAVY Index0.00

Boman Index0.00

Instability Index0.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0280923 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptomyces roseosporus [Bacterium]

FamilyLipopeptide antibiotic

Structure & Mods

Configside-chain cyclized peptide [Cyclic]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermDecanoylation

C-TermMacrocyclized C-terminus

Other ModsNon-standard residues/X at 6, 12, 13; Lipidation (Decanoylation)

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetGram-positive bacteria membrane

Half-LifeClinical/Human: 8-9 h (up to 28 h in renal impairment)