Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 18.2

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC132H223N41O53S7

DescriptionStandard

        TGPQTTCQASTCEAGCKQIGKSMKSCQGDTCECA
    

Molecular Weight3456.88 Da

Isoelectric Point (pI)5.84

Net Charge (pH 7.0)-0.66

Net Charge (pH 7.4) -0.94

Charge Density (pH 7.0) -0.0193

GRAVY Index-0.54

Hydrophobic Moment 0.59

Boman Index-0.10

Instability Index30.99

Aliphatic Index 20.29

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1538.99

LogP -26.60

H-bond Donors 58.0

H-bond Acceptors 60.0

Rotatable Bonds 117.0

Heavy Atoms 233.0

Ring Count 1.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0027958 VERIFIED: NO

Provenance & Taxonomy

OrganismTityus discrepans [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-26; 12-31; 16-33

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0380559 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 29.4%, E 14.7%, T 23.5%, C 32.4% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic