Peptide Database

Peptide NameLactoferrampin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC105H176N30O26

DescriptionStandard

        LIWKLLSKAQEKFGKNKSR
    

Molecular Weight2274.71 Da

Isoelectric Point (pI)10.58

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.2504

GRAVY Index-0.89

Hydrophobic Moment 0.58

Boman Index-0.27

Instability Index33.27

Aliphatic Index 87.37

Aromaticity 0.1053

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 958.85

LogP -7.17

H-bond Donors 34.0

H-bond Acceptors 31.0

Rotatable Bonds 83.0

Heavy Atoms 161.0

Ring Count 3.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0229492 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyLactoferrampin

Tax ID9913

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetCandida albicans

MethodMIC

PaperLactoferrampin, an antimicrobial peptide of bovine lactoferrin, exerts its candidacidal activity by a cluster of positively charged residues at the C-terminus in combination with a helix-facilitating N-terminal part | Van Der Kraan, MIA. et al. | DOI: 10.1515/BC.2005.017 Evidence URLhttps://www.uniprot.org/uniprotkb/P24627/entry