Peptide Database

Peptide NameLaronidase

Function Ontology

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length255 amino acids

Chemical FormulaC1304H1965N373O370S6

DescriptionStandard

        APHLVQVDAARALWPLRRFWRSTGFCPPLPHSQADQYVLSWDQQLNLAYVGAVPHRGIKQVRTHWLLELVTTRGSTGRGLSYNFTHLDGYLDLLRENQLLPGFELMGSASGHFTDFEDKQQVFEWKDLVSSLARRYIGRYGLAHVSKWNFETWNEPDHHDFDNVSMTMQGFLNYYDACSEGLRAASPALRLGGPGDSFHTPPRSPLSWGLLRHCHDGTNFFTGEAGVRLDYISLHRKGARSSISILEQEKVVAQQ
    

Molecular Weight28979.22 Da

Isoelectric Point (pI)6.98

Net Charge (pH 7.0)-0.07

Net Charge (pH 7.4) -1.01

Charge Density (pH 7.0) -0.0003

GRAVY Index-0.43

Hydrophobic Moment 0.85

Boman Index-0.00

Instability Index37.11

Aliphatic Index 77.65

Aromaticity 0.1176

Extinction Coeff. Reduced 57410.00

Extinction Coeff. Oxidized 57535.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0173420 VERIFIED: YES

Provenance & Taxonomy

OrganismCricetulus griseus [Animal]

FamilyEnzyme

Tax ID10029

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme replacement

Half-Life1.5-3.6 h