MYP_136287
Dosotamide E
Antimicrobial
Standard
6 amino acids
C34H52N8O8
Standard
WLVING
700.83 Da
5.53
-0.24
-0.44
-0.0400
1.28
0.16
0.67
3.85
178.33
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
267.70
-0.20
9.0
8.0
20.0
50.0
2.0
6.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0003474
VERIFIED: YES
Provenance & Taxonomy
Bacteria [Bacterium]
2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0158424
VERIFIED: YES
Provenance & Taxonomy
Streptomyces nov [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
APD analysis reveals that the sequence of Dosotamide A shows 83.3% similarity to bacterial Dosotamide A. Active against B. subtilis. The third position is a D-amino acid. I4 is an L-allo-Ile
Bio-Activity Profile
Antimicrobial
Bacillus subtilis. The third position is a D-amino acid. I4 is an L-allo-Ile
RECORD: Rec_0179214
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)