Peptide Database

Peptide NameDefensin 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC353H554N106O104S10

DescriptionStandard

        MARSISLVSIFVFFLLLAATGPSMVAEARDCESQSHKFKGTCLSDTNCASVCQTERFTGGHCRGFRHRCFCTTHC
    

Molecular Weight8267.47 Da

Isoelectric Point (pI)8.52

Net Charge (pH 7.0)2.78

Net Charge (pH 7.4) 2.23

Charge Density (pH 7.0) 0.0370

GRAVY Index0.11

Hydrophobic Moment 0.67

Boman Index0.03

Instability Index34.73

Aliphatic Index 59.87

Aromaticity 0.0933

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3365.31

LogP -41.10

H-bond Donors 130.0

H-bond Acceptors 121.0

Rotatable Bonds 270.0

Heavy Atoms 573.0

Ring Count 12.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0279763 VERIFIED: NO

Provenance & Taxonomy

OrganismLens culinaris [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal