Peptide Database

Peptide NameD-Magainin-NH2 II

Function Ontology

Antimicrobial

Antiparasitic ▸ Antimalarial

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC109H171N29O28

DescriptionStandard

        GIGKFLHSAKKFGKAFVGEINS
    

Molecular Weight2335.70 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.59

Charge Density (pH 7.0) 0.1294

GRAVY Index0.00

Hydrophobic Moment 0.69

Boman Index0.15

Instability Index-0.56

Aliphatic Index 75.45

Aromaticity 0.1364

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 928.03

LogP -8.13

H-bond Donors 32.0

H-bond Acceptors 32.0

Rotatable Bonds 81.0

Heavy Atoms 166.0

Ring Count 4.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0249488 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus laevis [Animal]

FamilyMagainin

Tax ID8355

Structure & Mods

Configlinear peptide [Linear]

Chiralityall-D amino-acid peptide [D]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Antimalarial

TargetPlasmodium falciparum F32 Tanzania

MethodPercent inhibition; Microscopy (Acridine orange staining)