Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length56 amino acids

Chemical FormulaC273H425N73O85S6

DescriptionStandard

        MAKFNDFDLDLVQTPKQSNQIEPQWKSQSFCTPGCVTGVLQTCFIQTATCNCHISK
    

Molecular Weight6282.12 Da

Isoelectric Point (pI)6.49

Net Charge (pH 7.0)-0.46

Net Charge (pH 7.4) -0.81

Charge Density (pH 7.0) -0.0082

GRAVY Index-0.27

Hydrophobic Moment 0.39

Boman Index0.03

Instability Index70.03

Aliphatic Index 60.89

Aromaticity 0.0893

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2568.40

LogP -30.27

H-bond Donors 89.0

H-bond Acceptors 92.0

Rotatable Bonds 205.0

Heavy Atoms 437.0

Ring Count 10.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0176746 VERIFIED: YES

Provenance & Taxonomy

OrganismPaenibacillus nuruki [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria