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MYP_136251
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Basic Information
IB-367
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Standard
17 amino acids
C78H129N29O19S4
Standard
Sequence
RGGLCYCRGRFCVCVGR
Physicochemical Analysis
1905.30 Da
9.37
3.72
3.46
0.2188
0.24
0.30
-0.14
-7.18
57.06
0.1176
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
796.75
-9.00
35.0
27.0
61.0
130.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0155567 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
Paper抗菌肽IB-367的固相合成与抑菌活性; Solid Phase Synthesis and Anti-microbial Activities of the Antibacterial Peptide IB-367. [J].合成化学,2016,24(07):600-603. DOI:10.15952/j.cnki.cjsc.1005-1511.2016.07.16116. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37348
RECORD: Rec_0166922 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis KCTC 2213
PMID25445605 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25445605/
RECORD: Rec_0172202 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Protegrin
9823
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
5-14, 7-12
Bio-Activity Profile
Antibacterial Antifungal Anti-inflammatory Anti-mucositis
Pseudomonas aeruginosa (ATCC 9027)
2 μg/mL
MIC
PaperA phase III, randomized, double-blind, placebo-controlled, study of iseganan for the reduction of stomatitis in patients receiving stomatotoxic chemotherapy. Leukoc. Res.(2004) PMID15120931 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15120931/
RECORD: Rec_0175917 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella oxytoca KCTC 1686
PMID25445605 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25445605/
RECORD: Rec_0181666 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Micrococcus luteus KCTC9341
PMID25445605 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25445605/
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