Peptide Database

Peptide NameIB-367

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC78H129N29O19S4

DescriptionStandard

        RGGLCYCRGRFCVCVGR
    

Molecular Weight1905.30 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)3.72

Net Charge (pH 7.4) 3.46

Charge Density (pH 7.0) 0.2188

GRAVY Index0.24

Hydrophobic Moment 0.30

Boman Index-0.14

Instability Index-7.18

Aliphatic Index 57.06

Aromaticity 0.1176

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 796.75

LogP -9.00

H-bond Donors 35.0

H-bond Acceptors 27.0

Rotatable Bonds 61.0

Heavy Atoms 130.0

Ring Count 2.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0424765 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct based on Clinical trials [Synthetic]

FamilyProtegrin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial

TargetStaphylococcus spp. 35 strains

Activity0.13-4 μg/mL

MethodMIC

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