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MYP_136237
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Basic Information
Unnamed
Enzyme modulation ▸ Enzyme inhibition ▸ Amylase inhibition ▸ Alpha-amylase inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Glycosidase inhibition ▸ Alpha-glucosidase inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
5 amino acids
C29H54N8O6
Standard
Sequence
LPLLR
Physicochemical Analysis
610.79 Da
9.75
0.76
0.56
0.1520
1.06
0.62
0.15
85.04
234.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
232.83
0.25
8.0
7.0
18.0
43.0
1.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0044083 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic Alpha-amylase inhibitory
HepG2
2000.0
IC50
PaperWang J., Wu T., Fang L., Liu C., Liu X., Li H., Shi J., Li M., Min W.. Anti-diabetic effect by walnut (Juglans mandshurica Maxim.)-derived peptide LPLLR through inhibiting alpha-glucosidase and alpha-amylase, and alleviating insulin resistance of hepatic HepG2 cells. J. Funct. Foods, 69, 103944, 2020.
RECORD: Rec_0066751 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic
HepG2
PaperWang J., Wu T., Fang L., Liu C., Liu X., Li H., Shi J., Li M., Min W.. Anti-diabetic effect by walnut (Juglans mandshurica Maxim.)-derived peptide LPLLR through inhibiting alpha-glucosidase and alpha-amylase, and alleviating insulin resistance of hepatic HepG2 cells. J. Funct. Foods, 69, 103944, 2020.
RECORD: Rec_0302793 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic Alpha-glucosidase inhibitory
HepG2
2000.0
IC50
PaperWang J., Wu T., Fang L., Liu C., Liu X., Li H., Shi J., Li M., Min W.. Anti-diabetic effect by walnut (Juglans mandshurica Maxim.)-derived peptide LPLLR through inhibiting alpha-glucosidase and alpha-amylase, and alleviating insulin resistance of hepatic HepG2 cells. J. Funct. Foods, 69, 103944, 2020.
RECORD: Rec_0304694 VERIFIED: NO
Provenance & Taxonomy
Juglans mandshurica [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory