Peptide Database

Peptide NameFractalkine

Function Ontology

Binding / Molecular interaction ▸ Binding activity

Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC371H607N119O107S6

DescriptionStandard

        QHHGVTKCNITCSKMTSKIPVALLIHYQQNQASCGKRAIILETRQHRLFCADPKEQWVKDAMQHLDRQAAALTRNG
    

Molecular Weight8638.91 Da

Isoelectric Point (pI)9.56

Net Charge (pH 7.0)6.16

Net Charge (pH 7.4) 5.63

Charge Density (pH 7.0) 0.0810

GRAVY Index-0.55

Hydrophobic Moment 0.72

Boman Index-0.13

Instability Index39.71

Aliphatic Index 78.42

Aromaticity 0.0395

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3695.61

LogP -40.86

H-bond Donors 131.0

H-bond Acceptors 124.0

Rotatable Bonds 294.0

Heavy Atoms 603.0

Ring Count 11.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010273 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Familyintercrine delta family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-34; 12-50

Bio-Activity Profile

Function

Cytokine Growth factor intercrine delta family Chemokine-like Growth factor signaling Angiogenic Integrin-binding Host defense