‹ ›
MYP_136213
← PREVIOUS NEXT → BACK
Basic Information
MTSC22EK
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Standard
24 amino acids
C141H222N32O43S
Standard
Sequence
MTWEEWDKKIEEYTKKIEELIKKS
Physicochemical Analysis
3085.53 Da
5.19
-1.49
-1.73
-0.0620
-1.42
0.69
-0.29
55.54
65.00
0.1250
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1262.34
-5.93
44.0
43.0
111.0
217.0
5.0
23.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0020687 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1 BaL
PMID31805154;31277353 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31805154/
RECORD: Rec_0070113 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1 NL4-3 V38A
PMID31805154;31277353 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31805154/
RECORD: Rec_0080597 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Human T cell leukemia MT-2
PMID31805154;31277353 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31805154/
RECORD: Rec_0087205 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1 IIIB
PMID31805154;31277353 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31805154/
RECORD: Rec_0105505 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Fusion-inhibitory peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Anti-HIV-1 Fusion inhibition
HIV-1 NL4-3 | TZM-bl cells
0.0024±0.0003 μM
IC50
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperConserved Residue Asn-145 in the C-Terminal Heptad Repeat Region of HIV-1 gp41 is Critical for Viral Fusion and Regulates the Antiviral Activity of Fusion Inhibitors. | Geng X, Liu Z, Yu D, Qin B, Zhu Y, Cui S, Chong H, He Y. | Viruses. 2019 Jul 3;11(7):609. | DOI:10.3390/v11070609 | PMID:31277353 PMID31277353 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31277353/
1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 1 of 4