MYP_136204
Darobactin A
Anticancer
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Standard
7 amino acids
C47H59N11O11
Standard
WNWSKSF
954.04 Da
8.75
0.76
0.55
0.1084
-1.14
0.48
0.02
11.39
0.00
0.4286
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
379.07
-2.01
14.0
12.0
27.0
69.0
5.0
7.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0423874
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Pseudomonas aeruginosa PA14
16 μg/mL
MIC
RECORD: Rec_0424390
VERIFIED: YES
Provenance & Taxonomy
Photorhabdus khanii [Bacterium]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
APD analysis reveals that this sequence is most similar (44.4%) to bacteria Plantaricin JLA-9. Chemical modification: This is a unique peptide that forms a new class UCSS1c. Darobactin has an unusual structure with two fused rings that form post-translationally. There is an unusual ether bond that links C6 of aromatic W1 and beta-carbon of W3. A second carbon-carbon bond connects C7 of aromatic W3 and beta-carbon of basic K5
Bio-Activity Profile
Antimicrobial
E. cloacae ATCC 13047
32 μg/mL
MIC
Unspecified 6 h
Showing 2 records on this page · Page 8 of 8