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MYP_136204
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Basic Information
Darobactin A
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
7 amino acids
C47H59N11O11
Standard
Sequence
WNWSKSF
Physicochemical Analysis
954.04 Da
8.75
0.76
0.55
0.1084
-1.14
0.48
0.02
11.39
0.00
0.4286
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
379.07
-2.01
14.0
12.0
27.0
69.0
5.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0032317 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Darobactin-resistant Escherichia coli MG1655 mutant strain 1
128 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
RECORD: Rec_0035321 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli NRZ14408
4 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
RECORD: Rec_0049082 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0063551 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Darobactin-resistant Escherichia coli MG1655 mutant strain 2
128 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
RECORD: Rec_0064370 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii LAC-4
8 μg/mL
MIC
PMID34937193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34937193/
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