MYP_136191
Basic Information
Cecropin A (1-7)+Melittine (2-9) [5,12DHPhe]
Antimicrobial
Antimicrobial Antibacterial
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
not Standard
15 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KWKLXKKIGAVXKVL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0026391 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 5,12
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 11303
12.5 μM
MIC
RECORD: Rec_0236394 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 5,12
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 259230
18.75 μM
MIC
RECORD: Rec_0356243 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 5,12
Bio-Activity Profile
Hemolytic
mouse red blood cells
90 % hemolysis at 100 μM
Hemolysis