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MYP_136181
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Basic Information
Unnamed
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-III Inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
5 amino acids
C29H39N5O7
Standard
Sequence
YAGFL
Physicochemical Analysis
569.65 Da
5.52
-0.24
-0.45
-0.0482
1.34
0.22
0.72
55.36
98.00
0.4000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
199.95
0.23
7.0
7.0
15.0
41.0
2.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0274804 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Enkephalin
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Thiomethylene bond replacement between residue 3-4
Bio-Activity Profile
Analgesic
HPLC
Human serum, in vitro; >60000 s
PMID4034413 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4034413/
RECORD: Rec_0274874 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pentapeptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-melanogenic Antioxidant
Human dermal fibroblasts (NHDF) (In vitro)
Cell viability assay; Cytotoxicity assay; Immunostaining; qRT-PCR; Tyrosinase assay; Histology
PaperD-tyrosine adds an anti-melanogenic effect to cosmetic peptides PMID31937863 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31937863/
RECORD: Rec_0348010 VERIFIED: YES
Provenance & Taxonomy
Unknown [Animal]
DADLE
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for DADLE: PMID 10406217 PMID10406217 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10406217/
RECORD: Rec_0384089 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
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