Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length152 amino acids

Chemical FormulaC753H1181N219O220S7

DescriptionStandard

        MVSKVQFNPRSRTDAIFVHCSATKPEMDIGVETIRMWHKQQGWLDVGYHFIIKRDGTVEDGRPVNVVGSHVKDWNSRSVGVCLVGGIDAKGQFEANFTPAQMNSLRNKLADLKVLYPQAEIKAHHDVAPKACPSFDLQRWLSTNELVTSDRG
    

Molecular Weight17046.22 Da

Isoelectric Point (pI)8.48

Net Charge (pH 7.0)2.01

Net Charge (pH 7.4) 1.41

Charge Density (pH 7.0) 0.0132

GRAVY Index-0.39

Hydrophobic Moment 0.57

Boman Index-0.03

Instability Index43.51

Aliphatic Index 78.16

Aromaticity 0.0789

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7070.16

LogP -71.99

H-bond Donors 246.0

H-bond Acceptors 235.0

Rotatable Bonds 563.0

Heavy Atoms 1199.0

Ring Count 29.0

Amide Bonds 165.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0138596 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage vB_EcoP_PR_Kaz2018 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic