Peptide Database

Peptide NameBrevinin-2ISc (Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC139H246N38O47S2

DescriptionStandard

        SVLGTVKDLLIGAGKSAAQSVLTTLSCKLSNSC
    

Molecular Weight3265.80 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)1.44

Net Charge (pH 7.4) 1.20

Charge Density (pH 7.0) 0.0436

GRAVY Index0.61

Hydrophobic Moment 0.40

Boman Index0.20

Instability Index31.61

Aliphatic Index 118.18

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1378.13

LogP -18.89

H-bond Donors 51.0

H-bond Acceptors 51.0

Rotatable Bonds 112.0

Heavy Atoms 226.0

Ring Count 0.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416227 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana ishikawae [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

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