Peptide Database

Peptide NameProtegrin 3 (Protegrin-4)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length103 amino acids

Chemical FormulaC491H795N135O163S5

DescriptionStandard

        QALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRQPPELCDFKENGCVGTVTLDQIKDPLDITCNEVSGPLLVSSC
    

Molecular Weight11357.70 Da

Isoelectric Point (pI)4.55

Net Charge (pH 7.0)-6.26

Net Charge (pH 7.4) -6.57

Charge Density (pH 7.0) -0.0608

GRAVY Index-0.49

Hydrophobic Moment 0.77

Boman Index-0.09

Instability Index30.52

Aliphatic Index 83.20

Aromaticity 0.0388

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4781.92

LogP -53.13

H-bond Donors 163.0

H-bond Acceptors 162.0

Rotatable Bonds 368.0

Heavy Atoms 794.0

Ring Count 15.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0185766 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal