Peptide Database

Peptide NameInsulin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC156H240N44O40S3

DescriptionStandard

        AANRHLCGSHLVEALYLVCGNRGFFYIPSKM
    

Molecular Weight3468.04 Da

Isoelectric Point (pI)8.87

Net Charge (pH 7.0)1.95

Net Charge (pH 7.4) 1.63

Charge Density (pH 7.0) 0.0629

GRAVY Index0.30

Hydrophobic Moment 0.46

Boman Index0.17

Instability Index36.73

Aliphatic Index 91.29

Aromaticity 0.1290

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1339.11

LogP -10.87

H-bond Donors 49.0

H-bond Acceptors 47.0

Rotatable Bonds 110.0

Heavy Atoms 243.0

Ring Count 7.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046821 VERIFIED: YES

Provenance & Taxonomy

OrganismPolypterus senegalus [Animal]

FamilyInsulin

Tax ID55291

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour