Peptide Database

Peptide NameBeta-endorphin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC180H283N49O50S2

DescriptionStandard

        YGGFMKSWDERSQKPLLTLFKNVMIKDGHEKKGQ
    

Molecular Weight3997.60 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.58

Charge Density (pH 7.0) 0.0838

GRAVY Index-0.99

Hydrophobic Moment 0.58

Boman Index-0.17

Instability Index17.79

Aliphatic Index 54.41

Aromaticity 0.1176

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1636.71

LogP -13.61

H-bond Donors 56.0

H-bond Acceptors 56.0

Rotatable Bonds 140.0

Heavy Atoms 281.0

Ring Count 7.0

Amide Bonds 36.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0208551 VERIFIED: YES

Provenance & Taxonomy

OrganismAcipenser transmontanus [Animal]

FamilyBeta-endorphin

Tax ID7904

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min

RECORD: Rec_0273972 VERIFIED: NO

Provenance & Taxonomy

OrganismAcipenser transmontanus [Animal]

FamilyPOMC

Tax ID7904

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor

RECORD: Rec_0304358 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0385532 VERIFIED: NO

Provenance & Taxonomy

OrganismAcipenser transmontanus [Animal]; Polyodon spathula [Animal]; Polypterus senegalus [Animal]

FamilyEndorphin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide