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MYP_135910
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Basic Information
Brevinin-1Bd
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
24 amino acids
C122H198N28O26S2
Standard
Sequence
FLPAIAGVAAKFLPKIFCAISKKC
Physicochemical Analysis
2537.18 Da
9.70
3.74
3.50
0.1557
1.15
0.60
0.38
30.12
114.17
0.1250
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
839.35
-2.73
30.0
32.0
81.0
178.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0351436 VERIFIED: YES
Provenance & Taxonomy
Rana berlandieri [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
PaperJ. Goraya et al. / Eur. J. Biochem. 267 (2000) 894-900. Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens PMID10651828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10651828/
RECORD: Rec_0360563 VERIFIED: NO
Provenance & Taxonomy
Rana berlandieri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 7862826 B2 Evidence URLhttps://patents.google.com/patent/US7862826B2/en PatentUS 7862826 B2
RECORD: Rec_0400517 VERIFIED: YES
Provenance & Taxonomy
Rana berlandieri [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PMID10651828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10651828/
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