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MYP_135888
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Basic Information
Thanatin [T15S]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C102H177N35O27S3
Standard
Sequence
GSKKPVPIIYCNRRSGKCQRM
Physicochemical Analysis
2421.91 Da
10.47
5.74
5.50
0.2732
-0.90
0.48
-0.36
64.84
50.95
0.0476
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1038.37
-12.02
39.0
36.0
82.0
167.0
3.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0034751 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli
04-8 μg/mL
MIC
PMID18810542;21453736;23643614 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18810542/
RECORD: Rec_0040060 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella oxytoca
8 μg/mL
MIC
PMID18810542;21453736;23643614 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18810542/
RECORD: Rec_0041376 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii ATCC 19606
128 μg/mL
MIC
PMID18810542;21453736;23643614 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18810542/
RECORD: Rec_0065844 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Thanatin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
11-18
Bio-Activity Profile
Antimicrobial
Acinetobacter baumannii ATCC 19606 or 8 clincial strains
>128 μg/mL
MIC
PaperInteraction of antimicrobial peptide s-thanatin with lipopolysaccharide in vitro and in an experimental mouse model of septic shock caused by a multidrug-resistant clinical isolate of Escherichia coli.
RECORD: Rec_0077602 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
5 % hemolysis at 100 μg/mL
Hemolysis
PMID18810542;21453736;23643614 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18810542/
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