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MYP_135881
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Basic Information
D form of F3
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
34 amino acids
C166H289N53O44
Standard
Sequence
AKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKK
Physicochemical Analysis
3731.40 Da
10.82
8.79
8.59
0.2586
-1.71
0.66
-0.53
79.91
37.65
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1568.63
-16.33
51.0
53.0
123.0
263.0
8.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0027593 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
HMGN2-derived
9606
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Fluorescein/FITC labeling
None
N-term detail: Labelled with fluorescein with an amino-hexanoic a; lowercase source residues at positions 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34 denote stereochemical modification
Bio-Activity Profile
Cell-penetrating peptide
MDA-MB-435
Fluorescence-based uptake assay
PMID12032302 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12032302/
RECORD: Rec_0173983 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID12032302 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12032302/
RECORD: Rec_0178356 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
HMGN2-derived
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
None
N-term detail: Labelled with fluorescein with an amino-hexanoic a
Bio-Activity Profile
Cell-penetrating peptide
HL-60; MDA-MB-435
Fluorescence-based uptake assay
PMID12032302 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12032302/
RECORD: Rec_0230075 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
fluorescein with 6-aminohexanoic acid (Ahx) spacer
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID12032302 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12032302/
RECORD: Rec_0345636 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
fluorescein with 6-aminohexanoic acid (Ahx) spacer
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID12032302 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12032302/
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