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MYP_135872
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Basic Information
Cholecystokinin 4
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-III Inhibitory
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
4 amino acids
C29H35N5O7S
Standard
Sequence
WMDF
Physicochemical Analysis
597.68 Da
4.05
-1.24
-1.44
-0.3097
0.07
0.54
0.43
47.85
0.00
0.5000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
203.71
1.05
7.0
7.0
16.0
42.0
3.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0123608 VERIFIED: YES
Provenance & Taxonomy
Unknown [Animal]
Cholecystokinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine
Experimental: CCK tetrapeptide showed a half-life of 13 min in human plasma while its cleavage in rat plasma occurred at a very high rate (half-life of less than 1 min); Mammalian: 2.8 hour; Yeast: 3 min; E. coli: 2 min
PaperBiological effects of newly synthesized cholecystokinin analogs; Degradation of cholecystokinin octapeptide, related fragments and analogs by human and rat plasma in vitro PMID11044801;6291099 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11044801/
RECORD: Rec_0143827 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
9925.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-III Inhibitory
Dipeptidyl peptidase III
PaperDhanda S.; Singh H.; Singh J.. Hydrolysis of various bioactive peptides by goat brain dipeptidylpeptidase-III. Cell Biochem. Funct. 23, 3, 339-345, 2008.
RECORD: Rec_0144528 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Intestinal hormone
HPLC
Human plasma, in vitro; 780 s
PMID6291099 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6291099/
RECORD: Rec_0229336 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Gastrin/cholecystokinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Gastrointestinal Neuropeptide
PMID11044801 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11044801/
RECORD: Rec_0336697 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal]
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone