Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC929H1392N206O286S9

DescriptionStandard

        VDDLAEVDYSLNSLPAVFQPFIDLDLKGIVYPAGNYTDPPYAAAPFIIPDQSDSMLYLAFSEYFFQTSSFAYYSAGAFNTTISEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMFKLMATEMPIISLEQDSFTVEIQGSMEVFAVLPDSTNQSLFTMNITANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight20310.78 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-16.26

Net Charge (pH 7.4) -16.55

Charge Density (pH 7.0) -0.0889

GRAVY Index0.24

Hydrophobic Moment 0.55

Boman Index0.24

Instability Index45.14

Aliphatic Index 87.98

Aromaticity 0.1421

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7782.88

LogP -82.16

H-bond Donors 262.0

H-bond Acceptors 279.0

Rotatable Bonds 642.0

Heavy Atoms 1430.0

Ring Count 38.0

Amide Bonds 198.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012847 VERIFIED: NO

Provenance & Taxonomy

OrganismHemiprocne comata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria