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MYP_135860
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Basic Information
C6a
Antimicrobial
Antiviral
Antiviral ▸ Anti-Retrovirus ▸ Anti-Lentivirus ▸ Anti-FIV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
6 amino acids
C43H59N11O9
Standard
Sequence
DWVRWI
Physicochemical Analysis
874.00 Da
5.84
-0.24
-0.44
-0.0398
-0.18
0.92
0.11
89.65
113.33
0.3333
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
339.60
0.71
13.0
9.0
24.0
63.0
4.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0168376 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Feline immunodeficiency virus (FIV):inhibition of virus replication in lymphoid cells
0.06-0.15 μg/mL
IC50
PMID30240422 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30240422/
RECORD: Rec_0200478 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
FIV-M2(Feline immunodeficiency virus M2):inhibition of virus replication in MBM cells
0.15 μg/mL
IC50
PaperPubMed PMID: 12610147 PMID12610147 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12610147/
RECORD: Rec_0259478 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-FIV Entry inhibition
FIV-M2 (Feline immunodeficiency virus M2) | MBM cells
0.15 μg/mL
IC50
Mammalian: 1.1 h; Yeast: 3 min; E. coli: >10 h
PaperAntiviral activity and conformational features of an octapeptide derived from the membrane-proximal ectodomain of the feline immunodeficiency virus transmembrane glycoprotein. | Giannecchini S, Di Fenza A, D'Ursi AM, Matteucci D, Rovero P, Bendinelli M. | J Virol. 2003 Mar;77(6):3724-33. | DOI:10.1128/jvi.77.6.3724-3733.2003 | PMID:12610147 PMID12610147 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12610147/
RECORD: Rec_0401387 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 12610147 PMID12610147 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12610147/
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