Peptide Database

Peptide NameAntimicrobial peptide NK-lysin

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length145 amino acids

Chemical FormulaC686H1151N201O209S10

DescriptionStandard

        MTSRALLLLASALLGTPGLTFSGLNPESYDLATAHLSDGEQFCQGLTQEDLQGDLLTERERQGIACWSCRKILQKLEDLVGEQPNEATINEAASRVCRNLGLLRGACKKIMRTCLRLISRDILAGKKPQEVCVDIKLCKHKAGLI
    

Molecular Weight15879.35 Da

Isoelectric Point (pI)8.13

Net Charge (pH 7.0)1.62

Net Charge (pH 7.4) 1.15

Charge Density (pH 7.0) 0.0112

GRAVY Index-0.10

Hydrophobic Moment 0.89

Boman Index-0.02

Instability Index43.15

Aliphatic Index 105.03

Aromaticity 0.0276

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6639.98

LogP -68.40

H-bond Donors 238.0

H-bond Acceptors 223.0

Rotatable Bonds 549.0

Heavy Atoms 1106.0

Ring Count 11.0

Amide Bonds 156.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0125568 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

Tax ID9796

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Cytotoxic Non-hemolytic Non-ribosomal

MethodQualitative functional evidence