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MYP_135817
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Basic Information
M-poneritoxin-Ng1d (M-PONTX-Ng1d) (Poneratoxin) (Ponericin-W4)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
26 amino acids
C134H223N35O31S
Standard
Sequence
GIWGTALKWGVKLLPKLVGMAQTKKQ
Physicochemical Analysis
2852.49 Da
10.60
4.76
4.54
0.1829
0.03
0.62
0.15
2.18
105.00
0.0769
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1070.35
-5.73
37.0
37.0
97.0
201.0
5.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0350032 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
S. aureusLMA
PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0370386 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
E. coli CIP 548
PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0386997 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
E. coliL
PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0391210 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Insecticidal Antifungal
Listeria ivanovii LMA 94d(Inhibition zone = 10mm)
PaperPonericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii. J Biol Chem. 2001 May 25;276(21):17823-9. doi: 10.1074/jbc.M100216200. PMID: 11279030. PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0400232 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Lactococcus lactis ssp. cremoris I116
PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
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