Peptide Database

Peptide NameM-poneritoxin-Ng1d (M-PONTX-Ng1d) (Poneratoxin) (Ponericin-W4)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Insecticidal/Pest control ▸ Insecticidal activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC134H223N35O31S

DescriptionStandard

        GIWGTALKWGVKLLPKLVGMAQTKKQ
    

Molecular Weight2852.49 Da

Isoelectric Point (pI)10.60

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.1829

GRAVY Index0.03

Hydrophobic Moment 0.62

Boman Index0.15

Instability Index2.18

Aliphatic Index 105.00

Aromaticity 0.0769

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1070.35

LogP -5.73

H-bond Donors 37.0

H-bond Acceptors 37.0

Rotatable Bonds 97.0

Heavy Atoms 201.0

Ring Count 5.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0003010 VERIFIED: YES

Provenance & Taxonomy

OrganismNeoponera goeldii [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Yeast Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Hemolytic Insecticidal

TargetGram-negative and Gram-positive bacteria

RECORD: Rec_0006849 VERIFIED: YES

Provenance & Taxonomy

OrganismPachycondyla goeldii [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Insecticidal Antifungal

TargetEnterobacter cloacae CIP 6085(Inhibition zone = 16.5mm)

RECORD: Rec_0006966 VERIFIED: YES

Provenance & Taxonomy

OrganismPachycondyla goeldii [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Insecticidal Antifungal

TargetSalmonella enterica CIP 813(no detected)

RECORD: Rec_0017723 VERIFIED: YES

Provenance & Taxonomy

OrganismPachycondyla goeldii [Animal]

FamilyPonericin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetMicrococcus luteus CIP 5345

RECORD: Rec_0021498 VERIFIED: YES

Provenance & Taxonomy

OrganismPachycondyla goeldii [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Insecticidal Antifungal

TargetProteus mirabilis LMA TP(no detected)

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