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MYP_135754
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
30 amino acids
C142H235N37O35S2
Standard
Sequence
GAFGNFLKGVAKKAGLKILSIAQCKLFGTC
Physicochemical Analysis
3084.74 Da
9.90
4.74
4.50
0.1578
0.63
0.62
0.26
-14.08
101.00
0.1000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1163.96
-9.63
42.0
42.0
107.0
216.0
3.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018896 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0042558 VERIFIED: YES
Provenance & Taxonomy
Rana nigrovittata [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
24-30
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans ATCC2002
MIC
PMID21171145 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21171145/
RECORD: Rec_0126437 VERIFIED: YES
Provenance & Taxonomy
Rana nigrovittata [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
24-30
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus ATCC2592
6.25 μg/mL
MIC
PMID21171145 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21171145/
RECORD: Rec_0155470 VERIFIED: YES
Provenance & Taxonomy
Rana nigrovittata [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
24-30
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus ATCC43300
6.25 μg/mL
MIC
PMID21171145 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21171145/
RECORD: Rec_0182445 VERIFIED: YES
Provenance & Taxonomy
Rana nigrovittata [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
24-30
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus subtilis
12.5 μg/mL
MIC
PMID21171145 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21171145/
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