‹ ›
MYP_135723
← PREVIOUS NEXT → BACK
Basic Information
Onc270
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
19 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
VDKPPYLPRPRPPRRIXNR
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0011076 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
3,5-diiodotyrosine at 17; 3,5-diiodotyrosine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC25922
16 μg/mL
MIC
PMID34902208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34902208/
RECORD: Rec_0027546 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
X=3‐Nitrotyrosine
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperEffect of Amino Acid Substitutions on 70S Ribosomal Binding, Cellular Uptake, and Antimicrobial Activity of Oncocin Onc112. Chembiochem. 2022 Mar 4;23(5):e202100609. doi: 10.1002/cbic.202100609. PMID: 34902208. PMID34902208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34902208/
RECORD: Rec_0031818 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
X=3,5‐Diiodotyrosine
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HepG2 (38% Killing=600 μg/ml)
PaperEffect of Amino Acid Substitutions on 70S Ribosomal Binding, Cellular Uptake, and Antimicrobial Activity of Oncocin Onc112. Chembiochem. 2022 Mar 4;23(5):e202100609. doi: 10.1002/cbic.202100609. PMID: 34902208. PMID34902208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34902208/
RECORD: Rec_0049822 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
3,5-diiodotyrosine at 17; 3,5-diiodotyrosine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa DSM1117
128 μg/mL
MIC
PMID34902208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34902208/
RECORD: Rec_0060599 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
3-nitrotyrosine at 17; 3-nitrotyrosine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae DSM681
8 μg/mL
MIC
PMID34902208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34902208/
1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 1 of 4