Peptide Database

Peptide Namep457-496

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC185H313N57O64S

DescriptionStandard

        IVHVTAKDKGTGKENTIRIQEGSGLSKEDIDRMIKDAEAH
    

Molecular Weight4391.87 Da

Isoelectric Point (pI)6.07

Net Charge (pH 7.0)-1.05

Net Charge (pH 7.4) -1.38

Charge Density (pH 7.0) -0.0264

GRAVY Index-0.83

Hydrophobic Moment 0.75

Boman Index-0.19

Instability Index-3.73

Aliphatic Index 80.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1995.21

LogP -23.04

H-bond Donors 69.0

H-bond Acceptors 66.0

Rotatable Bonds 158.0

Heavy Atoms 307.0

Ring Count 2.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0064122 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Fusion inhibitor

TargetPM-1

MethodQualitative inhibition

RECORD: Rec_0254157 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 30.0%, E 25.0%, T 10.0%, C 35.0% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial